A 286982 ( —— )

Catalog No. M24194 CAS No. 280749-17-9

A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

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2MG	39	In Stock
5MG	61	In Stock
10MG	98	In Stock
25MG	200	In Stock
50MG	332	In Stock
100MG	494	In Stock
200MG	Get Quote	In Stock
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Biological Information

Product Name

A 286982
Note

Research use only, not for human use.
Brief Description

A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1.
Description

A 286982 is an inhibitor that blocks the integrin-ligand interaction between leukocyte function-associated antigen-1 (LFA-1) and intercellular adhesion molecule-1.
Synonyms

——
Pathway

Cell Cycle/DNA Damage
Target

Integrin
Recptor

LFA-1;ICAM-1
Research Area

——
Indication

——

Chemical Information

CAS Number

280749-17-9
Formula Weight

453.6
Molecular Formula

C24H27N3O4S
Purity

>98% (HPLC)
Solubility

DMSO:<45.35 mg/mL (100mM)
SMILES

O=C(N1CCN(C(C)=O)CC1)/C=C/C2=CC=C(SC3=CC=CC=C3C(C)C)C([N+]([O-])=O)=C2
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1.Liu G, Link JT, Pei Z, et al. Discovery of novel p-arylthio cinnamides as antagonists of leukocyte function-associated antigen-1/intracellular adhesion molecule-1 interaction. 1. Identification of an additional binding pocket based on an anilino diaryl sulfide lead. J Med Chem. 2000;43(21):4025-4040. doi:10.1021/jm0002782

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